A new research study found that the antioxidant properties in green tea aid termination of antibiotic-resistant bacteria. The researchers found that epigallocatechin (EGCG) can be restored the activity of aztreonam, which is an antibiotic mainly used to treat infections triggered by pseudomonas aeruginosa.
Pseudomonas aeruginosa is related to bloodstream infections and serious respiratory tract that has become a major class for antibiotics in the coming years. At present, the combination of antibiotics is used to fight Pseudomonas aeruginosa. Therefore, these infections are becoming difficult to treat due to resistance of antibiotics has been noted.
To assess the aztreonam and EGCG, the researchers have conducted a vitro test to analyze how these bacteria interacted with the bacterial pathogens in groups or individually. Researchers also found that the combination of EGCG and aztreonam was expected to be more effective than single ones.
The study also revealed that EGCG with an antibiotic called aztreonam was effective in killing pseudomonas aeruginosa in tests and live organism test by using moth larvae.
A lead author of the study, Jonathan Betts said that antimicrobial-resistant (AMR) is a serious risk to public health across the world. The success of medical treatments is compromised without effective antibiotics treatments. He also said that to fight against AMR, it is necessary to develop novel antibiotics.
As per the new research study, Roberto La Ragione said that the WHO has also listed antibiotic-resistant (AMR) pseudomonas aeruginosa, a major risk to human health. He also states that it can successfully remove such risks with the help of natural products in combination with antibiotics. The further development of these alternatives to antibiotics would allow them to be used in the clinical settings for the near future.